One of the best party games I have played is "Scattergories".
The object of the game is to come up with an answer for each category with the letter rolled that nobody else playing comes up with.
One of the most fun things about the game is that joke answers are allowed. For example, if the category is "State" and the letter is "C", a perfectly acceptable answer would be confusion as "I am in the state of confusion".
It is also a good game because it can work with guys or girls (or both) and if you have players that are different ages they can all still play.
It also doesn't require a lot of set up and can be played just about anywhere.
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